Basic Information
VIS ID
TVIS30000678
Fusion event
HIV-TYW5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
200798810/199934087 (Hg38)
End
200798810/199934087 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
TYW5
miRNAs that regulate target gene
hsa-mir-93-5p ; hsa-mir-3144-3p ; hsa-mir-4266 ; hsa-mir-4495 ; hsa-mir-875-5p ; hsa-mir-6888-5p ; hsa-mir-1179 ; hsa-mir-1252-3p ; hsa-mir-3646 ; hsa-mir-129-5p ; hsa-mir-505-3p ; hsa-mir-3121-5p
Nearest miRNA
hsa-mir-10b/Upstream/10800976; hsa-mir-1244-1/Downstream/6849147;
Nearest TSS
ENST00000437798/Upstream/22781; ENST00000469156/Downstream/21230;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/22262, chr2-CpG: 61/Downstream/21243
Upstream sequence
CTTTATTTTCAATTGAATCTAAACATTTTCAGAATATAGGTGCTAGAGGAATACTAAAGCAATACCACAATATAACAAAGATGGAACACTAATCACAGGA
Downstream sequence
AAAACCCTTTTAATCCTGTGAAAGGGAGATTTAAATTTTAGAAACTTATTCTAAGAGTGTTTAAGGAAAAACAAAAGCTTAACATTTTGATTTGGAAAAC
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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