Basic Information
VIS ID
TVIS30000683
Fusion event
HIV-ZNF148 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr3
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
124944654/125225810 (Hg38)
End
124944654/125225810 (Hg38)
Orient
-
Location type
UTR3
Target gene
ZNF148
miRNAs that regulate target gene
hsa-mir-203a-3p ; hsa-mir-335-5p ; hsa-mir-186-5p ; hsa-mir-132-3p ; hsa-mir-181a-5p ; hsa-mir-93-5p ; hsa-mir-425-5p ; hsa-let-7b-5p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-513a-5p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-3681-3p ; hsa-mir-369-3p ; hsa-mir-5692a ; hsa-mir-155-5p ; hsa-mir-629-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-136-5p ; hsa-mir-885-5p ; hsa-mir-5680 ; hsa-mir-488-5p ; hsa-mir-365a-3p ; hsa-mir-365b-3p ; hsa-mir-6505-5p ; hsa-mir-6806-5p ; hsa-mir-4765 ; hsa-mir-4693-3p ; hsa-mir-4774-5p ; hsa-mir-4490 ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-5586-3p ; hsa-mir-514a-5p ; hsa-mir-618 ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-9-3p ; hsa-mir-6775-3p ; hsa-mir-1291 ; hsa-mir-7976 ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-4484 ; hsa-mir-6768-3p ; hsa-mir-548an ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a
Nearest miRNA
hsa-let-7g/Upstream/74258; hsa-mir-12124/Downstream/564594;
Nearest TSS
ENST00000440867/Upstream/12946; ENST00000610060/Downstream/7471;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/12907, chr3-CpG: 24/Downstream/131578
Upstream sequence
AAGATTGGAGAAGTATCATGTAGAATATCTCCCCTCCCCTCTCCCCACCATTCCTAATCATTCAAGAAAAACTGGGATCTAGGAAATGCATTAGTAGACT
Downstream sequence
ATCAGTGGTATTATTATGTAcaattggttaaagcaccatgctaataataaggccagggtcctaggactgatcattgcgagggccaattagtttaaatttg
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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