Basic Information
VIS ID
TVIS30000688
Fusion event
HIV-INPP4B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
143348166/142427013 (Hg38)
End
143348166/142427013 (Hg38)
Orient
-
Location type
Intronic
Target gene
INPP4B
miRNAs that regulate target gene
hsa-mir-222-3p ; hsa-mir-181a-5p ; hsa-mir-765
Nearest miRNA
hsa-mir-12113/Upstream/16919706; hsa-mir-1305/Downstream/916447;
Nearest TSS
ENST00000502981/Upstream/21753; ENST00000514766/Downstream/4246;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/789843, chr4-CpG: 111/Downstream/418774
Nearest cancer related gene
INPP4B(TSG, No orient, 0)
Upstream sequence
CTTCCTTACTGAATTTCTTTTTCCTAGAATTTGTTCTTGTTTTACTTCTGATTAAATAAATATGCACACCCTTAAACATGATAAAAATATTTAAGAAGCT
Downstream sequence
ATTATTCTTTCATTGGGAAATGAATAGAAGTTACTCATACAATAATAGGTGACGTCGGAGGATTTGTGGAATTAAAAAATCTCAAAGAAAAAAATGACAA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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