Basic Information
VIS ID
TVIS30000689
Fusion event
HIV-SAP30 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr4
Cytoband
q34.1
Reference genome
GRCh37/hg19
Start
174295299/173374148 (Hg38)
End
174295299/173374148 (Hg38)
Orient
+
Location type
Intronic
Target gene
SAP30
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-92a-3p ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-513b-5p ; hsa-mir-125b-2-3p ; hsa-mir-4457 ; hsa-mir-4773 ; hsa-mir-382-5p ; hsa-mir-212-3p
Nearest miRNA
hsa-mir-12113/Upstream/105915; hsa-mir-1305/Downstream/1049647;
Nearest TSS
ENST00000502981/Upstream/3205; ENST00000505032/Downstream/25388;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2026, chr4-CpG: 21/Downstream/126048
Upstream sequence
TTTTAAACTATTTGAACTATCTGCACAACCGAGAGGTTATTAAGTGCTAATGGAAGTTTTAATGTAGTGTATGTAACAGTACATTTTAATTAGAAAGAAC
Downstream sequence
AAAGTTAAAAAATCTGTTGTGGAAGAATCTAGTTGTGTAGAAATGTTTGTCTGCCACTTAGGAAATTCCTTTTTGTAATGACTGCTTAGTAGATTGTGTA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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