Basic Information
VIS ID
TVIS30000695
Fusion event
HIV-GEMIN5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr5
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
154295632/154916072 (Hg38)
End
154295632/154916072 (Hg38)
Orient
+
Location type
Intronic
Target gene
GEMIN5
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-34a-5p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-1303 ; hsa-mir-877-3p ; hsa-mir-324-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-10397/Upstream/86532; hsa-mir-103a-1/Downstream/5558330;
Nearest TSS
ENST00000502646/Upstream/23422; ENST00000519059/Downstream/15644;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/57270, chr5-CpG: 55/Downstream/21816
Upstream sequence
aatttgaatgtcatttaattgtggaatggatacattatggtaagcccatataatggaatgaacaggtaactgttttttttttaatttttattttttgtat
Downstream sequence
aggtggggtctccctacattgcccaggctggtttcaaactcctggtctcaagctatccttccactatggcctcccaaagtgctaggattacaggtatgag
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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