Basic Information
VIS ID
TVIS30000699
Fusion event
HIV-UQCC2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr6
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
33673679/33705902 (Hg38)
End
33673679/33705902 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
UQCC2
miRNAs that regulate target gene
hsa-mir-320a
Nearest miRNA
hsa-mir-1236/Upstream/7668; hsa-mir-10398/Downstream/193233;
Nearest TSS
ENST00000381078/Upstream/7245; ENST00000526556/Downstream/5782;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/17441, chr6-CpG: 56/Downstream/5479
Upstream sequence
TTAATACATGCTTTAAATTACCTGATTTTGCATTCACACCTAATGAGATCACAGACGTTTTAGGACTAATAGCAGTGCTGGGTTTGAAAAGGCAGCAGTG
Downstream sequence
GGGACATTATGAAAAATTCAGCACTGCTCCCCAAATGTGAATAAAATAGATGTTCATCTGACGAGTGTCCTTTATAGCTCTATTTTTGCTCCTTTTGCAT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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