Basic Information
VIS ID
TVIS30000702
Fusion event
HIV-FBXL4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr6
Cytoband
q16.2
Reference genome
GRCh37/hg19
Start
99393590/98945714 (Hg38)
End
99393590/98945714 (Hg38)
Orient
+
Location type
Intronic
Target gene
FBXL4
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-4474-5p ; hsa-mir-5189-3p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4795-5p
Nearest miRNA
hsa-mir-10398/Upstream/921093; hsa-mir-1202/Downstream/178895;
Nearest TSS
ENST00000381078/Upstream/111122; ENST00000418945/Downstream/2212;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/97136, chr6-CpG: 85/Downstream/1712
Upstream sequence
ATTTATTATATTTTAGATATCCAGTTGTGATGGTAAAATACAAATGGATATGAGGATATCTTCCTCATATCCCAGGGAACACTTCTACAGCCATTTATCT
Downstream sequence
CTTAGATAACCATTTTTCTCTTAGAAACCAGGTACAGAACATCCTAAATCACAGGTGATGGGGAGAGACACACTACAGTTACTATGACACGGTGCAAAGT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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