Basic Information
VIS ID
TVIS30000707
Fusion event
HIV-DBNL integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr7
Cytoband
p13
Reference genome
GRCh37/hg19
Start
44094370/44054771 (Hg38)
End
44094370/44054771 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7D
Target gene
DBNL
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-26b-5p ; hsa-mir-193b-3p ; hsa-mir-222-3p ; hsa-let-7b-5p ; hsa-mir-3187-3p ; hsa-mir-3613-3p ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4455 ; hsa-mir-616-5p
Nearest miRNA
hsa-mir-1183/Upstream/2942; hsa-mir-10399/Downstream/18607;
Nearest TSS
ENST00000635602/Upstream/4527; ENST00000452661/Downstream/2022;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/9925, chr7-CpG: 27/Downstream/10376
Upstream sequence
atacacaaaattattgttaactataatttcccttctgtactattgaatactagaatttattccttctatttaactgtacttttgtacctgttaagcaact
Downstream sequence
tctcttcattttctctcccccatgcccttcccaacccctggtaaccagcattctactctctccctccatgatacccacttttttagctcccacatgagtg
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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