Basic Information
VIS ID
TVIS30000710
Fusion event
HIV-ZNF777 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
149138415/149441324 (Hg38)
End
149138415/149441324 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
ZNF777
miRNAs that regulate target gene
hsa-mir-296-3p ; hsa-mir-18a-3p ; hsa-mir-106b-5p
Nearest miRNA
hsa-mir-10399/Upstream/2063203; hsa-mir-153-2/Downstream/1797097;
Nearest TSS
ENST00000635602/Upstream/18649; ENST00000486744/Downstream/19799;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/8521, chr7-CpG: 216/Downstream/18146
Upstream sequence
catacattgtgggaatatagtttatgaaaaaggtaacatttcaatccagtggggaaGAGTTTAAAAGGAATGGAGACAACTGGCTTCCTGATTAGAAAGG
Downstream sequence
GAAAAAAGCTACTTCACATATTTCACATCAAACTCCTGATGAACAAAAAAATTTATGTATAAATAAGAAATTCATACCTAAGTTTTACAACTTTAAGCTG
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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