Basic Information
VIS ID
TVIS30000720
Fusion event
HIV-PLAA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr9
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
26939288/26939290 (Hg38)
End
26939288/26939290 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA9C
Target gene
PLAA
miRNAs that regulate target gene
hsa-mir-5089-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-1281 ; hsa-mir-186-3p ; hsa-mir-4698 ; hsa-mir-6504-3p ; hsa-mir-552-3p ; hsa-mir-4800-3p ; hsa-mir-1228-3p ; hsa-mir-1247-3p ; hsa-mir-25-5p ; hsa-mir-4327 ; hsa-mir-4468 ; hsa-mir-455-3p ; hsa-mir-4756-3p ; hsa-mir-6087 ; hsa-mir-6499-3p ; hsa-mir-6516-5p
Nearest miRNA
hsa-mir-101-2/Upstream/5427105; hsa-let-7a-1/Downstream/1924336;
Nearest TSS
ENST00000422679/Upstream/16057; ENST00000518614/Downstream/7693;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/46352, chr9-CpG: 72/Downstream/7559
Upstream sequence
atcctggctaacacggtgaaaccccatctctactaaaaatacaaaaaattagccaggtgtggtggcaggggcctgtagtcccagctactcgggaggctga
Downstream sequence
ggcaggagaatggcgtgaacccaagaggtggagcttgcagtgagccgagattgcgccactgcactccagcctgggccacagactgaaactccgtctcaaa
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
Curate