Basic Information
VIS ID
TVIS30000723
Fusion event
HIV-CIZ1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr9
Cytoband
q34.11
Reference genome
GRCh37/hg19
Start
130937918/128175639 (Hg38)
End
130937918/128175639 (Hg38)
Orient
+
Location type
Intronic
Target gene
CIZ1
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-326 ; hsa-mir-18a-5p ; hsa-let-7d-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-let-7a-1/Upstream/306144; hsa-mir-12126/Downstream/69082;
Nearest TSS
ENST00000422679/Upstream/6178; ENST00000635766/Downstream/1969;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/14773, chr9-CpG: 79/Downstream/15601
Nearest cancer related gene
CIZ1(TSG, No orient, 0)
Upstream sequence
TCAAATTGTGACCTCTGTAAAATTAGGACAGAGCCCGTGACCACTGACTCAAGggaccgtccagcctatgaaagtgtttgatttgctctccgtagggttt
Downstream sequence
gttttgtttcaattctgaactagctgttaacattttgaaattgggagatttcacatacaaacctggatttctggattcttcttaaaactaagagatcCAG
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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