Basic Information
VIS ID
TVIS30000729
Fusion event
HIV-EHMT1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
140632307/137737855 (Hg38)
End
140632307/137737855 (Hg38)
Orient
-
Location type
Intronic
Target gene
EHMT1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-30e-5p ; hsa-mir-125b-5p
Nearest miRNA
hsa-let-7a-1/Upstream/287769; hsa-mir-602/Downstream/100564;
Nearest TSS
ENST00000422679/Upstream/20928; ENST00000478940/Downstream/752;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/19626, chr9-CpG: 21/Downstream/14327
Upstream sequence
aagaaaagacactgttaacggaataaaaaggcacctgtggagtaggagaaaatatctgcaaatcctatgtctgatgaggaattactacccaaaatataca
Downstream sequence
aaaaaaatcccacaactcaacaataaaaacaacttgattaaaaaatcagcaaaggaggccgggtgcagtggcttgcgcctgtaatctcagcactttggga
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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