Basic Information
VIS ID
TVIS30000742
Fusion event
HIV-PA2G4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
56501861/56108077 (Hg38)
End
56501861/56108077 (Hg38)
Orient
+
Location type
Intronic
Target gene
PA2G4
miRNAs that regulate target gene
hsa-mir-146a-5p ; hsa-mir-24-3p ; hsa-mir-16-5p ; hsa-mir-744-5p ; hsa-mir-423-5p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-484 ; hsa-mir-324-5p ; hsa-mir-342-3p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-3611 ; hsa-mir-524-5p ; hsa-mir-6077 ; hsa-mir-520d-5p ; hsa-mir-4694-3p ; hsa-mir-7-5p ; hsa-mir-423-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/1770763; hsa-let-7i/Downstream/1086427;
Nearest TSS
ENST00000382841/Upstream/1384; ENST00000552528/Downstream/1792;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/2814, chr12-CpG: 50/Downstream/10000
Nearest cancer related gene
PA2G4(OG, No orient, 0)
Upstream sequence
atgatcatgccactgcactccagcctgggcaacaatgaaaccctgtctcacaaaagaaaaaggaaaaataaGCATTTGCTGTCCCCACAAAACAGATTAG
Downstream sequence
AATGCCAGGTAAAAAAGGATAAACACTGGACTTAATATTATAGGCATgtggtggcacatgcctgtaatcccagcactttgggaggccaaggtgggaggat
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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