Basic Information
VIS ID
TVIS30000746
Fusion event
HIV-TPCN1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
113691951/113254146 (Hg38)
End
113691951/113254146 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E ; FRA12D
Target gene
TPCN1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-23b-3p
Nearest miRNA
hsa-let-7i/Upstream/94969; hsa-mir-1178/Downstream/37377;
Nearest TSS
ENST00000382841/Upstream/9643; ENST00000548465/Downstream/6156;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/32294, chr12-CpG: 34/Downstream/80682
Upstream sequence
cccttatagctgtgtgatcttggacagattgtttagcctcttggcaaatttcttgaaagataaacaaaccaccaaagctttctcaataagaatagaaaac
Downstream sequence
ctgagtggccctatatgtactgaagaaggttaatatgtaataaaaactttcccagaaagaaaacttcaggcccagatagctttcctggtgaacggtatac
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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