Basic Information
VIS ID
TVIS30000753
Fusion event
HIV-DIAPH3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr13
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
60680597/60106463 (Hg38)
End
60680597/60106463 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B ; FRA13C
Target gene
DIAPH3
miRNAs that regulate target gene
hsa-mir-155-5p
Nearest miRNA
hsa-mir-1297/Upstream/4931915; hsa-mir-1267/Downstream/1093335;
Nearest TSS
ENST00000623511/Upstream/93157; ENST00000428656/Downstream/38235;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2471667, chr13-CpG: 52/Downstream/57063
Upstream sequence
actatgtggaaaaaaattggatccacatctcacatcaggcatagagatATATATTTCTAATAAttttaaatgaaaatataggagaatagatttatgatgt
Downstream sequence
caggatagatttcttcaataatatacaaaaaggacaaaccataaaaagtttgataaatctgaccacaattttacatttttgtacttcagctcccctttcc
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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