Basic Information
VIS ID
TVIS30000754
Fusion event
HIV-BORA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr13
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
73311449/72737311 (Hg38)
End
73311449/72737311 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B
Target gene
BORA
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-181d-5p
Nearest miRNA
hsa-mir-1297/Upstream/6518987; hsa-mir-1267/Downstream/4960701;
Nearest TSS
ENST00000623511/Upstream/9383; ENST00000489797/Downstream/44543;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/9295, chr13-CpG: 80/Downstream/44254
Upstream sequence
caacttgctctctggtcgtggaaggagtacgatttatagcgattcctgctatccatagtgtaagtactccaaccatggccagtttcaagctactgatgtg
Downstream sequence
acatcactgaatgggaaaggaagaatagtggcacaccattatatgtaggaattccaccatacagatacaaaatacattattaacctcaagagcatagaca
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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