Basic Information
VIS ID
TVIS30000757
Fusion event
HIV-ACIN1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr14
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
23543559/23074350 (Hg38)
End
23543559/23074350 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACIN1
miRNAs that regulate target gene
hsa-mir-340-5p ; hsa-mir-93-5p ; hsa-mir-18a-5p ; hsa-mir-1226-3p ; hsa-mir-93-3p ; hsa-mir-324-5p ; hsa-mir-106b-5p ; hsa-mir-221-3p ; hsa-mir-218-5p ; hsa-mir-7108-5p ; hsa-mir-1227-5p ; hsa-mir-3187-3p ; hsa-mir-663b ; hsa-mir-128-2-5p ; hsa-mir-128-1-5p ; hsa-mir-6845-5p ; hsa-mir-6762-5p ; hsa-mir-6877-5p ; hsa-mir-4529-5p ; hsa-mir-134-3p ; hsa-mir-7114-5p ; hsa-mir-6852-5p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-331-3p ; hsa-mir-4640-3p
Nearest miRNA
hsa-mir-4707/Upstream/117321; hsa-mir-1185-1/Downstream/314246;
Nearest TSS
ENST00000550708/Upstream/2733; ENST00000554203/Downstream/4520;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/16199, chr14-CpG: 78/Downstream/20419
Upstream sequence
ATTCCGAACATTTTATTTTCAGACAATAATGAGggccgggcatggtggctcacgcctgtaataccaacactttgggaggctgagacaggaggactgcctg
Downstream sequence
aggccaggagtttgagaccagcctggccaacatggtgaaaccccatctctattaaaaatagaaaaattagcagggtgtggcagccgcgtctatagtccca
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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