Basic Information
VIS ID
TVIS30000758
Fusion event
HIV-GNG2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr14
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
52336155/51869437 (Hg38)
End
52336155/51869437 (Hg38)
Orient
+
Location type
Intronic
Target gene
GNG2
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6881-3p ; hsa-mir-222-5p ; hsa-mir-942-5p ; hsa-mir-877-3p ; hsa-mir-16-1-3p
Nearest miRNA
hsa-mir-208a/Upstream/1569491; hsa-mir-1185-1/Downstream/2078990;
Nearest TSS
ENST00000550708/Upstream/8113; ENST00000556471/Downstream/8155;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/216667, chr14-CpG: 60/Downstream/119973
Upstream sequence
CTTATGTGGTAGCTGGATAATGTCCTTAGCAACCTGGATTCTTCCCTTCCTCCCACTGTGACACCTTCAGCAGGTTGATTTCCCCTCACTGTGTGGACAT
Downstream sequence
GGCGTCTACAATTTTGGAATTATAGGCATATTTCAATACGTAGAGGCATATCAAGGTGCAGCAGATTTCTTATGTGGCTCTTTCTGGtttgttgaaacag
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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