Basic Information
VIS ID
TVIS30000761
Fusion event
HIV-USP3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
63833770/63541571 (Hg38)
End
63833770/63541571 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
USP3
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-18a-3p ; hsa-mir-10b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-26a-5p ; hsa-mir-670-3p ; hsa-mir-4279 ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-mir-10393/Upstream/717530; hsa-mir-11181/Downstream/329359;
Nearest TSS
ENST00000557528/Upstream/4433; ENST00000558925/Downstream/3054;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/36132, chr15-CpG: 121/Downstream/59019
Upstream sequence
TATTTAAAAACAATATTTTGAAGTTTAAGAAGAAACTTTCTAATAGAGATAATCTTAAAACATAAAAGGCTCTTCCTTAAGATAAGCTGGTACTTGTCTG
Downstream sequence
CTTTTAACAAAGGATATGGGTTTGCTCTGCAGGTATTCTTCTAATTTTCCATAATTGGCTTATTTGATGGCAATACATCAGAGTTTAGTAAGAGAATTTA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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