Basic Information
VIS ID
TVIS30000764
Fusion event
HIV-LINS1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
101126873/100586668 (Hg38)
End
101126873/100586668 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINS1
miRNAs that regulate target gene
hsa-mir-26a-5p ; hsa-mir-129-5p ; hsa-mir-510-3p ; hsa-mir-2054 ; hsa-mir-380-3p ; hsa-mir-6873-3p ; hsa-mir-4279 ; hsa-mir-6867-3p ; hsa-mir-7111-3p ; hsa-mir-670-5p ; hsa-mir-4766-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-4319 ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-4732-3p ; hsa-mir-345-3p ; hsa-mir-488-3p ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-6888-3p ; hsa-mir-6740-3p ; hsa-mir-942-5p ; hsa-mir-3120-5p
Nearest miRNA
hsa-mir-10393/Upstream/1802166; hsa-mir-1302-10/Downstream/1373791;
Nearest TSS
ENST00000557528/Upstream/12827; ENST00000561192/Downstream/10268;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/27380, chr15-CpG: 80/Downstream/15102
Upstream sequence
ctaagaattctagttaacacataattctgtaaacaaaatgtgccaaaaagtttatattactagtgagaaaaataataattttgtctaattcagaagttat
Downstream sequence
ctaaaagttagttcagatacagatttgaaaaggttatttatgaaataccatagtaagaaaccagtaagtagcggataaacatgtggaaaaaatttatata
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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