Basic Information
VIS ID
TVIS30000768
Fusion event
HIV-XPO6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
28182077/28170756 (Hg38)
End
28182077/28170756 (Hg38)
Orient
-
Location type
Intronic
Target gene
XPO6
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-122-5p ; hsa-mir-324-5p ; hsa-mir-320a ; hsa-mir-185-5p ; hsa-mir-222-3p ; hsa-mir-181b-5p ; hsa-mir-16-5p ; hsa-mir-4260 ; hsa-mir-1227-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-6825-5p ; hsa-mir-3180 ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-3188 ; hsa-mir-1273e ; hsa-mir-7847-3p ; hsa-mir-885-3p ; hsa-mir-31-5p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-6820-5p ; hsa-mir-2467-3p ; hsa-mir-1827 ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-576-3p
Nearest miRNA
hsa-mir-1225/Upstream/2145446; hsa-mir-11401/Downstream/220226;
Nearest TSS
ENST00000527434/Upstream/855; ENST00000635780/Downstream/2366;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/106781, chr16-CpG: 100/Downstream/40444
Upstream sequence
AAACTTTGCATGCTTCAGAAAAGTTCATGATTAAATATAGCAGAGCAACACCATACATACATGTCATTAAACTAAGATTAGTTAGGATTTTGCAAATACC
Downstream sequence
CATGTAGCAAATTAAGTTGCTGTTTCTATCACGTGTAATAGTCTCTCTACCATAAGAAAGTTTAACTAAACAAGACAAAAAAAGTACGCCTTCAACAGCA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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