Basic Information
VIS ID
TVIS30000770
Fusion event
HIV-NLRC5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
GRCh37/hg19
Start
57036552/57002640 (Hg38)
End
57036552/57002640 (Hg38)
Orient
+
Location type
Intronic
Target gene
NLRC5
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-216b-5p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-452-3p ; hsa-mir-6504-5p ; hsa-mir-4736 ; hsa-mir-3064-5p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-3126-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-149-5p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-1225/Upstream/98287; hsa-mir-11401/Downstream/769649;
Nearest TSS
ENST00000527434/Upstream/13046; ENST00000538059/Downstream/1213;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/12784, chr16-CpG: 133/Downstream/89492
Nearby gene
NLRC5(+14434) ;
Upstream sequence
tgcagatatctctttgagacactgattcctttcttttgggtatatacctagcagtgggattgctggatcatatggtagctctaaatttagtttagttttt
Downstream sequence
ttttgttttttttttttttttgagacagagtctcactctgtctcaaggctggagtgcagtgcgtgatctcagttcactgcaacctctgcctcctgggttc
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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