Basic Information
VIS ID
TVIS30000778
Fusion event
HIV-MED13 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
60133653/62056292 (Hg38)
End
60133653/62056292 (Hg38)
Orient
-
Location type
Intronic
Target gene
MED13
miRNAs that regulate target gene
hsa-mir-208a-3p ; hsa-mir-151a-3p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-1303 ; hsa-mir-30c-5p ; hsa-mir-196a-5p ; hsa-mir-17-5p ; hsa-let-7b-5p ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-5580-3p ; hsa-mir-8084 ; hsa-mir-6831-3p ; hsa-mir-205-5p ; hsa-mir-5585-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-5585-3p ; hsa-mir-4708-5p ; hsa-mir-1253 ; hsa-mir-153-5p ; hsa-mir-95-5p ; hsa-mir-5197-3p ; hsa-mir-338-5p ; hsa-mir-5692a ; hsa-mir-3591-5p ; hsa-mir-4460 ; hsa-mir-4727-3p ; hsa-mir-4775 ; hsa-mir-7160-5p ; hsa-mir-3605-5p ; hsa-mir-3679-5p ; hsa-mir-1185-5p ; hsa-mir-27b-5p ; hsa-mir-6718-5p ; hsa-mir-203b-5p ; hsa-mir-590-3p ; hsa-mir-562 ; hsa-mir-140-5p ; hsa-mir-568 ; hsa-mir-4477a ; hsa-mir-3163 ; hsa-mir-595 ; hsa-mir-224-5p ; hsa-mir-4783-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485
Nearest miRNA
hsa-mir-10226/Upstream/2013187; hsa-mir-1250/Downstream/887923;
Nearest TSS
ENST00000595228/Upstream/22467; ENST00000635817/Downstream/8990;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/128237, chr17-CpG: 101/Downstream/8594
Upstream sequence
ACTGAGCCAAGTTTCTAATATCCTGACAATCTAATAACTGTAATAAAAGTACTTTCTACACGTTGTATTCAGATACGAAAAGTGAAATGGTACAACCAAC
Downstream sequence
CCACTCAAGGCATAGTGATATGCACTATTTACACTAATTGAAACAAGTTCTTGAATCTCAACACCAGCATTATAATAGGGAGGGGAAGGAGAAGGGAACA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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