Basic Information
VIS ID
TVIS30000781
Fusion event
HIV-SRP68 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
74050959/76054878 (Hg38)
End
74050959/76054878 (Hg38)
Orient
-
Location type
Intronic
Target gene
SRP68
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-320b ; hsa-mir-92b-3p ; hsa-mir-365a-3p ; hsa-mir-320a ; hsa-mir-221-3p ; hsa-mir-3653-5p ; hsa-mir-3140-5p ; hsa-mir-888-3p ; hsa-mir-3912-3p ; hsa-mir-548an
Nearest miRNA
hsa-mir-10226/Upstream/270271; hsa-mir-1250/Downstream/43141;
Nearest TSS
ENST00000595228/Upstream/1222; ENST00000329003/Downstream/5864;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/32301, chr17-CpG: 45/Downstream/17215
Upstream sequence
caccattgcacAACGCGTTAATAAAAACAGGATACAGAACTGTATCTTAGTATAATTCCAGCAAGGGAAAAAAAAACATAAGAACTCTCATGAATATAAA
Downstream sequence
AAACATTAAAAAGAAACAGTGCTTTCCTTTCAGTATGATGTCATATCAATGAAGGCATATAGGAAGTGAGACAATAGGCTGAtctttttttttttgagac
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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