Basic Information
VIS ID
TVIS30000784
Fusion event
HIV-RPTOR integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
78929533/80955733 (Hg38)
End
78929533/80955733 (Hg38)
Orient
+
Location type
Intronic
Target gene
RPTOR
miRNAs that regulate target gene
hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-155-5p
Nearest miRNA
hsa-mir-10226/Upstream/536240; hsa-mir-1250/Downstream/169543;
Nearest TSS
ENST00000595228/Upstream/7183; ENST00000572778/Downstream/5980;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/7300, chr17-CpG: 23/Downstream/5510
Upstream sequence
acgagttacagaatatatataaaaatatgtGCAACTGTCTGTCGTGAAAAAAAACGGCAAACACCACACATCGATAAGGATTTGGGGACATTGGCTTGTG
Downstream sequence
TGTGTCCTGCCGAGAGTGTAGATGGTCACCCATTTGGGGAATGAAATGGCCTTCCCTGGGGAGATCAGAGTCATGCAGGATACATGACTGGCAGTTCCGT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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