Basic Information
VIS ID
TVIS30000790
Fusion event
HIV-TMEM259 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1018490/1018491 (Hg38)
End
1018490/1018491 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
TMEM259
miRNAs that regulate target gene
hsa-mir-590-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1302-11/Upstream/204838; hsa-let-7e/Downstream/797668;
Nearest TSS
ENST00000633603/Upstream/1071; ENST00000562015/Downstream/2360;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3912, chr19-CpG: 72/Downstream/2021
Upstream sequence
AGCCACCCAGGCATGGGTGAGAGCTGGGGGACTCCATGCCAGCTCAGGGCTGGGAGCTCAGCTGCACAGATGCCACAGGATGAAGCCACCTTGAAGGGAT
Downstream sequence
CATACCAGGGAGGACCTGGCTCTCTGCAGGGAGACCCCCGGAAGCCAGGCAGGCAGGAAGCAGAGGAGCCTTCTGGAACTCAAGGCAGCCTCTGAAATCA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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