Basic Information
VIS ID
TVIS30000799
Fusion event
HIV-LIN37 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
36243634/35752733 (Hg38)
End
36243634/35752733 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
LIN37
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-193b-3p
Nearest miRNA
hsa-mir-10395/Upstream/407106; hsa-let-7e/Downstream/3656890;
Nearest TSS
ENST00000633603/Upstream/3948; ENST00000591163/Downstream/180;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3750, chr19-CpG: 109/Downstream/2850
Upstream sequence
GTCCCCCCGTGGTTGCCACCTAGACCCCCATGGGTATGGGTGGGACAAAAGGCCCAAGAGGCAAGTGGGGTTCATGTGAGCATCTCAGGTTTGATACCAG
Downstream sequence
TATCCCCAGGGTGCCCTCTGCAGGGTTTTGCACAGGCGTTTGTCTGAGGGTCAACTGTCTTTCCCCACAGGGACTGCTCCATCGCAGCCACTGGCAAAAG
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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