Basic Information
VIS ID
TVIS30000802
Fusion event
HIV-POLD1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50893504/50390247 (Hg38)
End
50893504/50390247 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
POLD1
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-mir-193b-3p ; hsa-mir-1-3p ; hsa-mir-34a-5p ; hsa-mir-324-5p ; hsa-let-7e-5p
Nearest miRNA
hsa-mir-10395/Upstream/457110; hsa-let-7e/Downstream/816682;
Nearest TSS
ENST00000633603/Upstream/5874; ENST00000596425/Downstream/12965;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/5571, chr19-CpG: 48/Downstream/11973
Upstream sequence
atccacccacctcagcctctcatagtgttgggattacaggtgtgagccactgcgcctggccAATAAtttctttttttcttttcttttctttttttttttt
Downstream sequence
caagttacatgaagtaaatttattatttacagctaggcaacaagggaaaaccgaagcataggattcattgtgagccaatctcccgagactcaggaaggtt
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
Curate