Basic Information
VIS ID
TVIS30000811
Fusion event
HIV-PRPF6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
62620265/63988912 (Hg38)
End
62620265/63988912 (Hg38)
Orient
-
Location type
Intronic
Target gene
PRPF6
miRNAs that regulate target gene
hsa-mir-1226-3p ; hsa-mir-149-5p ; hsa-mir-23b-3p ; hsa-mir-7977 ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4746-3p ; hsa-mir-4798-3p ; hsa-mir-6750-3p ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-1-1/Upstream/46186; hsa-mir-6813/Downstream/88043;
Nearest TSS
ENST00000382410/Upstream/7777; ENST00000444463/Downstream/45432;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/7478, chr20-CpG: 28/Downstream/40696
Upstream sequence
cagctgagatcgtgccattgcactccggcctgggcaacagagtgagactccgtctcaaaaaaaaaaaaagaaaaagaaaaaataattctaaaatgtacat
Downstream sequence
ggagccaaaaaagacccagaataggcaaagctatcctgagcaaaaggaacaaaactgggggaacacttgacttcaaattatactacagagctgtagtaac
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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