Basic Information
VIS ID
TVIS30000814
Fusion event
HIV-MORC3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr21
Cytoband
q22.12
Reference genome
GRCh37/hg19
Start
37724517/36352219 (Hg38)
End
37724517/36352219 (Hg38)
Orient
+
Location type
Intronic
Target gene
MORC3
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-101-3p ; hsa-mir-32-5p ; hsa-mir-21-5p ; hsa-mir-197-3p ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-218-2-3p ; hsa-mir-30e-3p ; hsa-mir-545-5p ; hsa-mir-584-5p ; hsa-mir-622 ; hsa-mir-758-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-144-3p ; hsa-mir-5700 ; hsa-mir-153-3p
Nearest miRNA
hsa-let-7c/Upstream/631411; hsa-mir-3197/Downstream/3094791;
Nearest TSS
ENST00000624081/Upstream/4347; ENST00000484028/Downstream/9617;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/31458, chr21-CpG: 63/Downstream/32979
Upstream sequence
agtatagttcatcatattgatgtttaataagagaaagcccttatggtcatatacatagatagagaaaaagcacttgcaattatttttaaaaggaacacct
Downstream sequence
acaaaaactgtgaatcaaagggcataataacagagtatttacacacacacggcaagctacattactaatggggaacaattgatagctttccttagaaggg
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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