Basic Information
VIS ID
TVIS30000817
Fusion event
HIV-POLR2F integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr22
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
38358801/37962794 (Hg38)
End
38358801/37962794 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
POLR2F
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-1296-5p ; hsa-mir-378a-5p ; hsa-mir-320a ; hsa-mir-4266 ; hsa-mir-4777-3p ; hsa-mir-3164 ; hsa-mir-6820-3p ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-550a-3p ; hsa-mir-200c-5p ; hsa-mir-7106-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-505-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-3663-5p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-4302 ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-1207-5p ; hsa-mir-1237-5p ; hsa-mir-1909-3p ; hsa-mir-1910-3p ; hsa-mir-2682-5p ; hsa-mir-3144-5p ; hsa-mir-3191-3p ; hsa-mir-34b-5p ; hsa-mir-3665 ; hsa-mir-4488 ; hsa-mir-449c-5p ; hsa-mir-4652-5p ; hsa-mir-4697-5p ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-486-3p ; hsa-mir-6511a-5p ; hsa-mir-6721-5p ; hsa-mir-6722-3p ; hsa-mir-6806-5p ; hsa-mir-6808-5p ; hsa-mir-6810-5p ; hsa-mir-6846-5p ; hsa-mir-6848-5p ; hsa-mir-6893-5p ; hsa-mir-940
Nearest miRNA
hsa-mir-1286/Upstream/115020; hsa-let-7a-3/Downstream/4769;
Nearest TSS
ENST00000624155/Upstream/9067; ENST00000427034/Downstream/20620;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/8832, chr22-CpG: 83/Downstream/20292
Upstream sequence
atttaattttttttgagacggagtcttgctctgtcacccaggctggagtgcagtggcacagtcttggctcactgcaagctctgcctcacgggttcacgcc
Downstream sequence
attctcctgcctcagccttcccagtagctgggaccacaggcacctgccaccacgcccggctaattttttgtagttttagtagagatggtgtttcaccgtg
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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