Basic Information
VIS ID
TVIS30000818
Fusion event
HIV-RBX1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
41363962/40967958 (Hg38)
End
41363962/40967958 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
RBX1
miRNAs that regulate target gene
hsa-mir-92a-3p ; hsa-mir-194-5p ; hsa-mir-6875-3p ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-642a-5p ; hsa-mir-188-3p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-5187-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p
Nearest miRNA
hsa-mir-1286/Upstream/154000; hsa-let-7a-3/Downstream/124555;
Nearest TSS
ENST00000624155/Upstream/1757; ENST00000637592/Downstream/123828;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/16203, chr22-CpG: 111/Downstream/53719
Upstream sequence
GACAACAGAGAGTGGGAATTCCAAAAGTAGGTATCTTTGGTTGTTTTGACGGGGCTTTTTGACTTGCCTCAGGCTGAAAGGAGCGTGGTCTTGGGGGATG
Downstream sequence
GAGACATGATACATGCCTTGTTTTTTTTAAAACTAGTTTTTGGTTACTTAAGCTAGGACTTATCTATATGGAAAATGCACAAAGGATTAGCCAACATTAG
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
Curate