Basic Information
VIS ID
TVIS30000819
Fusion event
HIV-NDUFA6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
42482848/42086844 (Hg38)
End
42482848/42086844 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
NDUFA6
miRNAs that regulate target gene
hsa-mir-2113 ; hsa-mir-218-5p ; hsa-mir-568 ; hsa-mir-921 ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-591 ; hsa-mir-520f-5p ; hsa-mir-3174
Nearest miRNA
hsa-mir-1281/Upstream/163547; hsa-let-7a-3/Downstream/3114110;
Nearest TSS
ENST00000624155/Upstream/7144; ENST00000626627/Downstream/491;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/6754, chr22-CpG: 87/Downstream/3501
Upstream sequence
CTTCCAGCTGTAAACTGGCATTCAGATGAAGTGGTAACTTCTAGGGATGAGGTTCAAGAAGAGTTCAAACTTTCCTCCCTATATCTTTTTTTATGGTTAT
Downstream sequence
AAAATGCAAGTCCCAGTGGATGTTCCCTTGATGAATCTTATCTATTTAACCAGATGATAACCTCCAAGTTCAAGTATTTCTCTGAAACACAGCAATAATC
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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