Basic Information
VIS ID
TVIS30000827
Fusion event
HIV-FUNDC2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chrX
Cytoband
q28
Reference genome
GRCh37/hg19
Start
154263042/155034767 (Hg38)
End
154263042/155034767 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRAXE ; FRAXF
Target gene
FUNDC2
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-193b-3p ; hsa-mir-339-5p ; hsa-mir-186-5p ; hsa-mir-4303 ; hsa-mir-921 ; hsa-mir-633 ; hsa-mir-4682 ; hsa-mir-3174 ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-2053 ; hsa-mir-3613-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p
Nearest miRNA
hsa-let-7f-2/Upstream/147309; hsa-mir-1184-2/Downstream/348333;
Nearest TSS
ENST00000429181/Upstream/1341; ENST00000471528/Downstream/12290;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/7346, chrX-CpG: 73/Downstream/36020
Upstream sequence
attttgccaggctattaaatttttaaaaaattagttaatttttccttagcgaggtaatcaagttaaatccagactataaaaattttaccagtctggtagt
Downstream sequence
taggtagtagtatttcatggtggcttcatttacatttccctgagtaggagtgacattgatcgacttttacgtatgtttgttgaccatttggatctcctct
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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