Basic Information
VIS ID
TVIS30000828
Fusion event
HIV-MACO1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
25768302/25441811 (Hg38)
End
25768302/25441811 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
MACO1
miRNAs that regulate target gene
hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-6832-3p ; hsa-mir-627-3p
Nearest miRNA
hsa-mir-12136/Upstream/418225; hsa-mir-101-1/Downstream/464551;
Nearest TSS
ENST00000473358/Upstream/10891; ENST00000470035/Downstream/7082;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/10187, chr1-CpG: 109/Downstream/101591
Upstream sequence
ttggggttagggcggcttattgtgaggaagtgatatttgtgctgtgtgccgaaggatgagtagCTATGGAAGTGCTTCATTTAGTTTTAATTGTACTTAG
Downstream sequence
GTAGGGATCTTGGCTTTGACTCAGAAAGAAATGTAGAAAAATGGAAGAACTAACCCTGAACAGTTTGAATGTTCCCAGTTATGAGAAGGACAGTCAACCA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
Curate