Basic Information
VIS ID
TVIS30000832
Fusion event
HIV-DENND2C integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
115142538/114599917 (Hg38)
End
115142538/114599917 (Hg38)
Orient
-
Location type
Intronic
Target gene
DENND2C
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-6768-5p ; hsa-mir-8485 ; hsa-mir-4276 ; hsa-mir-143-5p ; hsa-mir-6499-3p ; hsa-mir-5190 ; hsa-mir-570-3p ; hsa-mir-510-3p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-1228-3p ; hsa-mir-127-5p ; hsa-mir-25-3p ; hsa-mir-25-5p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-377-5p ; hsa-mir-4325 ; hsa-mir-4459 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4786-3p ; hsa-mir-6086 ; hsa-mir-6087 ; hsa-mir-6516-5p ; hsa-mir-658 ; hsa-mir-7703 ; hsa-mir-7843-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-101-1/Upstream/1717788; hsa-mir-1182/Downstream/1960107;
Nearest TSS
ENST00000473358/Upstream/11360; ENST00000468191/Downstream/25408;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/88274, chr1-CpG: 65/Downstream/69701
Upstream sequence
TCCATGCCACTATATACCACTAGATAACTGAGAGACTGATCCTACATTTCAAAAATATGCCCAAATTTTtgttctcactcataggtgggaattgaacaat
Downstream sequence
gagaacacttggacacagggtagggaacatcacacaccggggcctgtcgtggggtggggggatggggggagggctagcattaggagaaatacctaatgta
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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