Basic Information
VIS ID
TVIS30000844
Fusion event
HIV-EVC2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr4
Cytoband
p16.2
Reference genome
GRCh37/hg19
Start
5674956/5673229 (Hg38)
End
5674956/5673229 (Hg38)
Orient
-
Location type
Intronic
Target gene
EVC2
miRNAs that regulate target gene
hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-3942-3p ; hsa-mir-6873-3p ; hsa-mir-5100 ; hsa-mir-4722-5p ; hsa-mir-6721-5p ; hsa-mir-942-5p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-5088-3p ; hsa-mir-6729-3p ; hsa-mir-4768-3p ; hsa-mir-1245b-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p
Nearest miRNA
hsa-mir-4800/Upstream/3423073; hsa-mir-12113/Downstream/250046;
Nearest TSS
ENST00000502981/Upstream/235312; ENST00000514919/Downstream/35338;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/104605, chr4-CpG: 56/Downstream/35029
Upstream sequence
GTATACTTTACCACACACACAGAAACAGTGCCTAATGTTTAGGGTTATGGTACACAGAAGTCAGAAAATCTGAGCCGCTATTGCTACTACTGTTGTTGGC
Downstream sequence
TGGTGGGAAGGGCACAGATCAGGAGACACAGTCAACAGAGTGTTGTGATGGAATGTATATGTAAGAAGCCAGACACAGGAGGAGCCAACAATGTCCCTGA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
Curate