Basic Information
VIS ID
TVIS30000846
Fusion event
HIV-ZNF827 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr4
Cytoband
q31.22
Reference genome
GRCh37/hg19
Start
146824251/145903099 (Hg38)
End
146824251/145903099 (Hg38)
Orient
+
Location type
Exonic
Target gene
ZNF827
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-16-5p ; hsa-mir-218-5p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-1252-5p ; hsa-mir-6730-5p ; hsa-mir-5584-5p ; hsa-mir-6873-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4311 ; hsa-mir-3180-5p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-4744 ; hsa-mir-466 ; hsa-mir-4643 ; hsa-mir-144-3p ; hsa-mir-4789-3p ; hsa-mir-101-3p
Nearest miRNA
hsa-mir-12113/Upstream/2559564; hsa-mir-1305/Downstream/505484;
Nearest TSS
ENST00000502981/Upstream/10684; ENST00000510331/Downstream/35372;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/141434, chr4-CpG: 161/Downstream/33083
Upstream sequence
CCAGTGCCACCAGCTCCAACGTGTGGCTGCTGGGAGTCGTGCTTCCCAAGGAGGTGTCCGGGGACGTGGACTGCTCCTGGATCCGGTCCTCCAGAGACAA
Downstream sequence
CTTATAGTTCTCCTGGACTTCCCCATAGGATGCTTCTGACGGAGTCTCTGAAGAGTTTCCATACCAGTGTTCTCCTTCACTGAGCTCTCCCTCCGCCTCT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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