Basic Information
VIS ID
TVIS30000851
Fusion event
HIV-NT5C3A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
33059398/33019786 (Hg38)
End
33059398/33019786 (Hg38)
Location type
Intronic
Target gene
NT5C3A
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-122-5p ; hsa-mir-16-5p ; hsa-mir-320a ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-6504-3p ; hsa-mir-499b-3p ; hsa-mir-499a-3p ; hsa-mir-144-3p
Nearest miRNA
hsa-mir-1183/Upstream/286709; hsa-mir-10399/Downstream/1920974;
Nearest TSS
ENST00000635602/Upstream/3860; ENST00000482941/Downstream/7247;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/61807, chr7-CpG: 80/Downstream/42540
Upstream sequence
AAGCTTGCTGAACAAGCAAACCATGTGATTTAGTATACCTGGAGTTTATGACCAAAGGAAAAAAGACTATCAATTAAGACAAACTAAAATTATTATCTTT
Downstream sequence
ATTACAAAACATTCTTCCATGTGAGAAAATCTGTTCCTCATATTTGGATTTAAATTTTAGAGATTGAAGTTCATCACTAATGAATGTATACCTCATGTCT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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