Basic Information
VIS ID
TVIS30000860
Fusion event
HIV-PSMA1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
14552052/14530506 (Hg38)
End
14552052/14530506 (Hg38)
Orient
+
Location type
Intronic
Target gene
PSMA1
miRNAs that regulate target gene
hsa-mir-659-3p ; hsa-mir-218-1-3p ; hsa-mir-5701 ; hsa-mir-4772-3p ; hsa-mir-891b ; hsa-mir-520h ; hsa-mir-3973 ; hsa-mir-520g-3p ; hsa-mir-548l
Nearest miRNA
hsa-mir-210/Upstream/2366739; hsa-let-7a-2/Downstream/1439027;
Nearest TSS
ENST00000527297/Upstream/9810; ENST00000532740/Downstream/113111;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/9827, chr11-CpG: 133/Downstream/113001
Upstream sequence
TTTACTTTCTTGGAGCCTCAGCCAAACTGAGACAGAAAGAGTCCCTTTTAAAATGCAACTACACATATAAAGCTTAattgcacttatttgttcatatgtt
Downstream sequence
gtcctcacattaaatcaggagccgctggaggataatgtttcatatttatctttgtacatatgtttaatgtgtcacactgactcgatgctcaataaaattt
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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