Basic Information
VIS ID
TVIS30000861
Fusion event
HIV-METTL15 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
28148365/28126818 (Hg38)
End
28148365/28126818 (Hg38)
Orient
+
Location type
Intronic
Target gene
METTL15
miRNAs that regulate target gene
hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6809-3p ; hsa-mir-4753-3p ; hsa-mir-942-5p ; hsa-mir-130b-5p ; hsa-mir-141-5p ; hsa-mir-6836-3p ; hsa-mir-5001-3p ; hsa-mir-6516-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-6728-3p ; hsa-mir-766-3p ; hsa-mir-4267 ; hsa-mir-3607-5p ; hsa-mir-216b-5p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-323a-3p ; hsa-mir-4735-5p
Nearest miRNA
hsa-mir-210/Upstream/69908; hsa-let-7a-2/Downstream/350663;
Nearest TSS
ENST00000527297/Upstream/16503; ENST00000468295/Downstream/200763;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/16144, chr11-CpG: 25/Downstream/1889307
Upstream sequence
tactggatatgcaatatagaacaaaattagacatggtcttagcccttaaggagcttacaatttagtggttgaaatgggcatttatcaagtaattattcaa
Downstream sequence
gtgaatatgaaatttccactgccatgaaagagtatatagtgctcttagatctccgaacaggaggatttaaagtggtaagattttcttgagtgggaagtaa
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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