Basic Information
VIS ID
TVIS30000862
Fusion event
HIV-C11orf49 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
47001492/46979941 (Hg38)
End
47001492/46979941 (Hg38)
Orient
+
Location type
Intronic
Target gene
C11orf49
miRNAs that regulate target gene
hsa-mir-1972 ; hsa-mir-3909 ; hsa-mir-4717-5p ; hsa-mir-6834-3p ; hsa-mir-6852-3p
Nearest miRNA
hsa-mir-129-2/Upstream/226749; hsa-let-7a-2/Downstream/199670;
Nearest TSS
ENST00000527297/Upstream/43161; ENST00000529980/Downstream/71982;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/43099, chr11-CpG: 93/Downstream/196535
Upstream sequence
ggtggaggttgcagtgagccgcgatcacgccactacactccagcctgggtgacaacagcgagactctgacttaaaataaaaaaGATTCTGTAGTTTCTGG
Downstream sequence
CACTTGAAATTGCAGGACTCCAACCTACAAATGCTGTATTATTATGAGATTTAGGCTGGAAATACTGAGGCAGTAGGATTTAAGCACTTACCCTTAATTG
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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