Basic Information
VIS ID
TVIS30000878
Fusion event
HIV-ASF1B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
14242164/14131352 (Hg38)
End
14242164/14131352 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
ASF1B
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-26b-5p ; hsa-mir-214-3p ; hsa-mir-130b-5p ; hsa-mir-92b-3p ; hsa-mir-18a-3p ; hsa-mir-324-5p ; hsa-mir-3677-5p ; hsa-mir-3133
Nearest miRNA
hsa-mir-10395/Upstream/57873; hsa-let-7e/Downstream/398191;
Nearest TSS
ENST00000633603/Upstream/12246; ENST00000588658/Downstream/5201;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/12900, chr19-CpG: 143/Downstream/4735
Upstream sequence
cagctcactgcaacctctgcctcccgggttctagcgattcttctgcctcagcctcctgagtagctgggattatagctgcgtgccaccatgcctggctaat
Downstream sequence
ttttgtatttagtagagccggggtttcaccacgtcggttaggctggtctcgaactcctgaccttgtgatccatccgcctcggcctcccaaagtgctggga
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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