Basic Information
VIS ID
TVIS30000888
Fusion event
HIV-UBA2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28086908
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh38/hg38
Start
34452847 (Hg38)
End
34452847 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
UBA2
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-941 ; hsa-mir-330-5p ; hsa-mir-93-3p ; hsa-mir-484 ; hsa-mir-181a-5p ; hsa-mir-34a-5p ; hsa-mir-100-5p ; hsa-mir-99a-5p ; hsa-mir-26a-5p ; hsa-mir-133a-3p ; hsa-mir-5096 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-197-3p ; hsa-mir-4716-5p
Nearest miRNA
hsa-mir-10395/Upstream/14053493; hsa-let-7e/Downstream/669853;
Nearest TSS
ENST00000633603/Upstream/2563; ENST00000588585/Downstream/5867;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/23792, chr19-CpG: 209/Downstream/28302
Upstream sequence
TGTGGTGTTGAAGATTAGTCATGGGTCTTAAGGCATAAAGGCCAATTTTAGAAACCTAAGAAAAATTTGTGTGTACATATTTTGAAACTTTGGTTGAATC
Downstream sequence
AGACATCTAAATACACTAAAATGAAGCTAGTATATTTAGATTCTTGGGATTCTTATAAACATTAGTCTCTTGGGTTTTGTGATATTTAAAGGGTAACTTT
Reference
Symons, J., et al. HIV integration sites in latently infected cell lines: evidence of ongoing replication. Retrovirology,2017, 14(1): 2.
Curate