Basic Information
VIS ID
TVIS30000893
Fusion event
HIV-DEAF1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28086908
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh38/hg38
Start
685243 (Hg38)
End
685243 (Hg38)
Orient
-
Location type
Intronic
Target gene
DEAF1
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-324-5p ; hsa-mir-100-5p ; hsa-mir-25-3p ; hsa-mir-218-5p ; hsa-mir-210-3p
Nearest miRNA
hsa-mir-210/Upstream/117045; hsa-let-7a-2/Downstream/571362;
Nearest TSS
ENST00000527297/Upstream/272; ENST00000488769/Downstream/2693;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/24562, chr11-CpG: 211/Downstream/9321
Upstream sequence
gcacgttctcggctcagtgcaacctctgcctccccggcgcaagcaattctcatgcctcggcctcccaagaagctgggattataggtttgcaccaccacac
Downstream sequence
ccagctaatttttgtatttttagtagagacaggttttgccatgttgaccaggctggtctcgaactcctggcctcaagcaatctgcccgcctcggcctccc
Reference
Symons, J., et al. HIV integration sites in latently infected cell lines: evidence of ongoing replication. Retrovirology,2017, 14(1): 2.
Curate