Basic Information
VIS ID
TVIS30000894
Fusion event
HIV-CBX5 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.13
Reference genome
End
54257973 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-1-3p ; hsa-mir-484 ; hsa-mir-339-5p ; hsa-mir-320a ; hsa-mir-197-3p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-345-5p ; hsa-mir-4795-3p ; hsa-mir-1343-3p ; hsa-mir-6716-5p ; hsa-mir-6783-3p ; hsa-mir-6852-5p ; hsa-mir-6736-3p ; hsa-mir-548p ; hsa-mir-4438 ; hsa-mir-4635 ; hsa-mir-488-3p ; hsa-mir-583 ; hsa-mir-4650-5p ; hsa-mir-1304-5p ; hsa-mir-6878-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-6721-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-4763-3p ; hsa-mir-6781-3p ; hsa-mir-1207-5p ; hsa-mir-2682-3p ; hsa-mir-4721 ; hsa-mir-3616-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-548at-5p ; hsa-mir-376a-2-5p ; hsa-mir-202-3p ; hsa-mir-6831-5p ; hsa-mir-4668-3p ; hsa-mir-3927-3p ; hsa-let-7a-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7g-5p ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-mir-4500 ; hsa-let-7f-5p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-4477a ; hsa-mir-4316 ; hsa-mir-1294 ; hsa-mir-4677-3p ; hsa-mir-16-1-3p ; hsa-mir-126-5p ; hsa-mir-5683 ; hsa-mir-370-5p ; hsa-mir-383-3p ; hsa-mir-3065-3p ; hsa-mir-5089-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-4252 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-3937 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-512-3p ; hsa-mir-449b-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-6771-5p ; hsa-mir-7977 ; hsa-mir-566 ; hsa-mir-4743-5p ; hsa-mir-4268 ; hsa-mir-6720-3p ; hsa-mir-20b-3p ; hsa-mir-6746-5p ; hsa-mir-4267 ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-4256 ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-4735-5p ; hsa-mir-6742-3p ; hsa-mir-939-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-1180-5p ; hsa-mir-1343-5p ; hsa-mir-2110 ; hsa-mir-3150a-3p ; hsa-mir-3175 ; hsa-mir-3908 ; hsa-mir-450a-2-3p ; hsa-mir-509-3p ; hsa-mir-6763-5p ; hsa-mir-6810-5p ; hsa-mir-6825-5p ; hsa-mir-6857-5p ; hsa-mir-7114-3p ; hsa-mir-7973 ; hsa-mir-92a-1-5p ; hsa-mir-939-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/26497; hsa-let-7i/Downstream/79243;
Nearest cancer related gene
CBX5(TSG, No orient, 0)
Upstream sequence
AACTACAACCTCCTCTTCGGCTAAAGAGACCAAAATTATTAGAAGGCACAACTGTTTAACTCTTCTATTTCAGATTCCAAAAGACAAGTAGTGTGGTATG
Downstream sequence
TTATTCCTGGCTATGTTTGTAACTGTTTACAAGCCAGGAACTCAAACAGAAATGTGCAAAATCTTTAGTTAAATGAACCAAGATAAAATTAAAACCTTTT
Reference
Symons, J., et al. HIV integration sites in latently infected cell lines: evidence of ongoing replication. Retrovirology,2017, 14(1): 2.
Curate