Basic Information
VIS ID
TVIS30000895
Fusion event
HIV-FUBP1 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28086908
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.23
Reference genome
GRCh38/hg38
Start
7946384 (Hg38)
End
7946384 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
FUBP1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-615-3p ; hsa-mir-324-3p ; hsa-mir-222-3p ; hsa-mir-22-3p ; hsa-mir-218-5p ; hsa-let-7i-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-4787-3p ; hsa-mir-1277-5p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-12136/Upstream/1516488; hsa-mir-101-1/Downstream/920118;
Nearest TSS
ENST00000473358/Upstream/3219; ENST00000460192/Downstream/7907;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/3745, chr1-CpG: 62/Downstream/7549
Nearest cancer related gene
FUBP1(OG, No orient, 0)
Upstream sequence
atgtaaaaacaaatttaaaattttacatactcaaattcacacattatattaaatacatacaaatgctgtatatgttaagtacaattatattttatttctt
Downstream sequence
aatcctttaagtcattactgtccaaacacaaattatgcgaaattatctattgtaacaaatgaaatgaaagcaaaaaaataaattttctagataaaaatac
Reference
Symons, J., et al. HIV integration sites in latently infected cell lines: evidence of ongoing replication. Retrovirology,2017, 14(1): 2.
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