Basic Information
VIS ID
TVIS30000896
Fusion event
HIV-PPP5C integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28086908
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh38/hg38
Start
4381104 (Hg38)
End
4381104 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
PPP5C
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-99b-3p ; hsa-mir-615-3p
Nearest miRNA
hsa-mir-1227/Upstream/419592; hsa-let-7e/Downstream/64874;
Nearest TSS
ENST00000633603/Upstream/812; ENST00000587580/Downstream/9506;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/9149, chr19-CpG: 57/Downstream/19016
Upstream sequence
AAAAACAACTCTGTTTCCCCACCGGCctcctctccctctctctgttcccccagcctctctgtccccctgcctctctctgtcccctctctctgtccccttt
Downstream sequence
gcctctgtccccctgcctctctctatccccctgcctctctgttcccctgcctctgtctcccctgactctctctgtccccctgcctctctctcccatctct
Reference
Symons, J., et al. HIV integration sites in latently infected cell lines: evidence of ongoing replication. Retrovirology,2017, 14(1): 2.
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