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TVIS30000903
Basic Information
VIS ID
TVIS30000903
Fusion event
HIV-ARID1A integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
27027937/26701446 (Hg38)
End
27028281/26701446 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
ARID1A
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-101-3p
;
hsa-mir-221-3p
;
hsa-mir-98-5p
;
hsa-mir-877-3p
;
hsa-mir-296-3p
;
hsa-mir-181a-2-3p
;
hsa-mir-18a-3p
;
hsa-mir-193b-3p
;
hsa-mir-484
;
hsa-mir-324-3p
;
hsa-mir-331-3p
;
hsa-mir-92a-3p
;
hsa-let-7e-5p
;
hsa-mir-203a-3p
;
hsa-mir-324-5p
;
hsa-mir-891a-3p
;
hsa-mir-3688-5p
;
hsa-mir-4642
;
hsa-let-7a-2-3p
;
hsa-let-7g-3p
;
hsa-mir-144-3p
;
hsa-mir-3177-5p
;
hsa-mir-185-5p
;
hsa-mir-135b-3p
;
hsa-mir-561-5p
;
hsa-mir-583
;
hsa-mir-609
;
hsa-mir-765
;
hsa-mir-3173-3p
;
hsa-mir-4306
;
hsa-mir-3150b-3p
;
hsa-mir-4644
;
hsa-mir-4784
;
hsa-mir-6891-5p
;
hsa-mir-19a-5p
;
hsa-mir-19b-1-5p
;
hsa-mir-19b-2-5p
;
hsa-mir-507
;
hsa-mir-557
;
hsa-mir-450b-5p
;
hsa-mir-876-3p
;
hsa-mir-3680-3p
;
hsa-mir-4649-3p
;
hsa-mir-6134
;
hsa-mir-7162-3p
;
hsa-mir-488-3p
;
hsa-mir-5681a
;
hsa-mir-4666a-3p
;
hsa-mir-1182
;
hsa-mir-31-5p
;
hsa-mir-222-3p
;
hsa-mir-485-3p
;
hsa-mir-539-3p
;
hsa-mir-664a-3p
;
hsa-mir-1266-5p
;
hsa-mir-4518
;
hsa-mir-4695-3p
;
hsa-mir-6823-5p
;
hsa-mir-7641
;
hsa-mir-7854-3p
;
hsa-mir-218-5p
;
hsa-mir-127-5p
;
hsa-mir-3613-5p
;
hsa-mir-3664-3p
;
hsa-mir-6830-5p
;
hsa-mir-377-3p
;
hsa-mir-3190-3p
;
hsa-mir-3202
;
hsa-mir-4533
;
hsa-mir-4768-3p
;
hsa-mir-3618
;
hsa-mir-6730-5p
;
hsa-mir-4708-3p
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548ae-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-448
;
hsa-mir-196a-3p
;
hsa-mir-5692a
;
hsa-mir-153-3p
;
hsa-mir-4303
;
hsa-mir-5583-5p
;
hsa-mir-3129-3p
;
hsa-mir-4652-3p
;
hsa-mir-4743-3p
;
hsa-mir-628-5p
;
hsa-mir-7114-3p
;
hsa-mir-1180-5p
;
hsa-mir-4750-3p
;
hsa-mir-2681-5p
;
hsa-mir-3149
;
hsa-mir-6512-5p
Nearest miRNA
hsa-mir-12136/Upstream/146853; hsa-mir-101-1/Downstream/4037710;
Nearest TSS
ENST00000473358/Upstream/5042;
ENST00000524572/Downstream/26262;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/3916
,
chr1-CpG: 58/Downstream/86181
Nearest cancer related gene
ARID1A
(TSG, No orient, 0)
Target sequence
CCAACTGTTCAGAGCTTGTTCCTGTGAATCCCAGGAGAAAATAGCTTTGAGTTCCTTCAGTCCAGGGGAAGAAAGATGGTCTCAAGACCCCTGATTTATGTACAGAAAGCTGCCTTCATAACAAGCCAGCTATGGAAGCACAGATATGTAGCATCTTAGAGTGAGAAGGCCATGCAGACCAACTTCATTTTATTGATGAGGGAGAAAATGAAAAATAGAGAAAGCAAATGACCTGCCCAGGGTCACACAGCTTAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
B1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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