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TVIS30000905
Basic Information
VIS ID
TVIS30000905
Fusion event
HIV-ATXN2 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.12
Reference genome
GRCh37/hg19
Start
111958119/111520315 (Hg38)
End
111958751/111520315 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
ATXN2
miRNAs that regulate target gene
hsa-mir-1226-3p
;
hsa-let-7b-5p
;
hsa-mir-374b-3p
;
hsa-mir-4524b-5p
;
hsa-mir-4524a-5p
;
hsa-mir-4519
;
hsa-mir-4274
;
hsa-mir-6796-5p
;
hsa-mir-4507
;
hsa-mir-3940-5p
;
hsa-mir-6819-5p
;
hsa-mir-6812-5p
;
hsa-mir-6737-5p
;
hsa-mir-6793-5p
;
hsa-mir-6742-5p
;
hsa-mir-4472
;
hsa-mir-4447
;
hsa-mir-3151-5p
;
hsa-mir-491-5p
;
hsa-mir-6769b-5p
;
hsa-mir-6769a-5p
;
hsa-mir-6766-5p
;
hsa-mir-6756-5p
;
hsa-mir-6747-5p
;
hsa-mir-608
;
hsa-mir-4651
;
hsa-mir-4664-5p
;
hsa-mir-342-5p
;
hsa-mir-6508-3p
;
hsa-mir-4726-5p
;
hsa-mir-4640-5p
;
hsa-mir-202-3p
;
hsa-mir-98-5p
;
hsa-mir-4500
;
hsa-mir-4458
;
hsa-let-7i-5p
;
hsa-let-7g-5p
;
hsa-let-7f-5p
;
hsa-let-7e-5p
;
hsa-let-7d-5p
;
hsa-let-7c-5p
;
hsa-let-7a-5p
;
hsa-mir-6823-3p
;
hsa-mir-2114-3p
;
hsa-mir-7162-3p
;
hsa-mir-544b
;
hsa-mir-299-3p
;
hsa-mir-4293
;
hsa-mir-1273g-3p
;
hsa-mir-141-5p
;
hsa-mir-181a-2-3p
;
hsa-mir-2682-3p
;
hsa-mir-3691-3p
;
hsa-mir-4436b-5p
;
hsa-mir-4746-5p
;
hsa-mir-6509-3p
;
hsa-mir-6781-3p
Nearest miRNA
hsa-let-7i/Upstream/216106; hsa-mir-1178/Downstream/279519;
Nearest TSS
ENST00000382841/Upstream/348;
ENST00000547021/Downstream/630;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/101369
,
chr12-CpG: 204/Downstream/77493
Target sequence
ATAATCTCTGCCCTTGCAAATTTAGATATTTTTTAACAACTTAGAAGACAAAACCGGCCAGGCACAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACGAGGTGAAGAGATCGAGACTATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAGAAATTAGATGGGCATGGTAGCACGCGCCTATAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTG
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Sample Information
×
Sample name
B1
Sample type
PBMC
Gender
Female
CpG Island Information
×
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